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Dec 3, 2008
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Major U.S. Epidemics



1793
Philadelphia: more than 4,000 residents died from yellow fever.
1832
July–Aug., New York City: over 3,000 people killed in a cholera epidemic.
Oct., New Orleans: cholera took the lives of 4,340 people.
1848
New York City: more than 5,000 deaths caused by cholera.
1853
New Orleans: yellow fever killed 7,790.
1867
New Orleans: 3,093 perished from yellow fever.
1878
Southern states: over 13,000 people died from yellow fever in lower Mississippi Valley.
1916
Nationwide: over 7,000 deaths occurred and 27,363 cases were reported of polio (infantile paralysis) in America's worst polio epidemic.
1918
March–Nov., nationwide: outbreak of Spanish influenza killed over 500,000 people in the worst single U.S. epidemic.
1949
Nationwide: 2,720 deaths occurred from polio, and 42,173 cases were reported.
1952
Nationwide: polio killed 3,300; 57,628 cases reported.
1981–Dec. 2005:
Total estimated U.S. AIDS cases: 988,376; total estimated AIDS deaths: 550,394 (Centers for Disease Control).
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